Latest Study on Tysabri

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I will admit to being a bit surprised by the number of MS patients I have met who are on Tysabri, considering the incidents of PML that are associated with the drug. I recognize the improved quality of life associated with the drug, and I’m told it’s efficacy is superior to other disease modifying drugs; but according to my neurologist, the risks do not justify the benefit (and that the scuttlebutt among the medical community is that the risks are worse than officially reported).
The decision, of course, is up to each patient, but it’s important to have the most up to date information in order to make that decision. Here’s the latest from Biogen, the company that manufactures the drug, and it suggests the risk of PML increases the longer one is on Tysabri.
News Detail : National MS Society.
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1 comment
Tysabri is also known as natalizumab & is an anti-VLA-4 monoclonal antibody medicine approved by both the US FDA & Europe's EMEA.
Tysabri & therapeutic implications for cancer?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC27479...
Tysabri & stem cells?
http://www.ncbi.nlm.nih.gov/pubmed/19566481
http://www.ncbi.nlm.nih.gov/pubmed/18235044
http://www.ncbi.nlm.nih.gov/pubmed/18195093
and going back as far as 1993 with monkeys
http://www.pnas.org/content/90/20/9374.abstract
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